Experts weigh in on the Week 1 clash between the San Francisco 49ers and Seattle Seahawks. Key matchups and predictions highlight this NFC West showdown, setting the stage for an intense season opener.
Browsing: Week 1
The San Francisco 49ers face the Seattle Seahawks in Week 1 of the 2025 NFL season. Catch the live stream, TV channel details, start time, and latest betting odds for this fierce NFC West showdown on Niners Wire.